Besides the bleachers in the outfield, the third base line is the best spot. If you are only going to be at Wrigley Field once then you must sit in the outfield and hope to catch a home run ball.
The best seats at Wrigley are located in the Infield Field box sections. Located at field level down both the first and third base lines, the sights and sounds from these seats will make your Wrigley experience come to life. Look out for foul balls! It sounds cliché, but there isn't a bad seat in the house at Wrigley. Because of its old, minimalistic design, even the higher reaches of the Upper Deck offer a fantastic bird's-eye view of the game action that still makes you feel in tune with the ballgame.