A Delightfully Different Lower Manhattan Boutique Hotel Consider Duane Street Hotel your relaxing home away from home. Nestled amid the stylish shops, galleries, and eateries of Tribeca, this all-new New York Manhattan boutique hotel is the perfect embodiment of its eclectic surroundings. While the architecture and decor feature a high-end urban design, the relaxed, welcoming spirit suggests an intimate neighborhood hideaway. It's this unique character that sets this hotel apart from uninspiring lower Manhattan boutique hotels. Here, special touches such as a 24-hour personal concierge, daily housekeeping, and sweet treats at turndown offer gentle comfort from a cheerful staff eager to please.