NRG Stadium is about seven miles southwest of downtown Houston within the Houston Inner Loop of the southern portion of Interstate Loop 610. The area is known as the Houston Medical District and has really been built up thanks to the stadium being there.

The stadium is around 10-15 minutes from downtown Houston and is located by the Dental and Medical schools in Houston. You can take the inner loop freeway to get there and then take some of the side streets depending on where you are parking.

It's located in what's known as "the Medical District of Houston", which is located downtown. It's best to use a gps to map where your coming from, and get on the inner loop freeway, the buildings downtown are huge. It's way easier to use the freeway.

Public transport is virtually non-existent in Houston so it's best to get an Uber or Taxi between destinations.